Product Introduction: ITEL 25

ITEL 25 is a low-dose cardioselective beta-blocker tablet manufactured by Noel Pharma. Composed of 25mg of Atenolol, this tablet is indicated for the treatment of essential hypertension, chronic stable angina pectoris, and cardiac arrhythmias. By slowing heart rate, it reduces cardiac workload and blood pressure.

Primary Indications

• Management of essential hypertension (high blood pressure).
• Treatment of chronic stable angina pectoris.
• Control of cardiac arrhythmias.

Therapeutic Benefits

• Cardioselective Action: High affinity for beta-1 receptors minimizes respiratory side effects.
• Cardioprotection: Reduces myocardial oxygen demand, protecting against ischemic events.
• Gentle BP Regulation: Lower starting dose reduces the risk of initial dizziness and side effects.

Possible Side Effects

Common side effects may include:

• Bradycardia (slow heart rate) or cold extremities.
• Fatigue, dizziness, or headache.
• Mild gastrointestinal discomfort or muscle weakness.

How to Take ITEL 25

• Take the tablet daily, preferably in the morning, with or without food.
• Swallow the tablet whole with water. Do not crush or chew.
• Do not stop taking the drug abruptly, as it can cause rebound hypertension or angina.

Mechanism of Action

ITEL 25 contains Atenolol, which is a highly selective antagonist of beta-1 adrenergic receptors in the heart. It blocks the chronotropic and inotropic actions of catecholamines, leading to a decrease in heart rate, myocardial contractility, and cardiac output, lowering systemic blood pressure.

Safety Warnings

• Bradycardia: Monitor heart rate. Contraindicated in patients with cardiogenic shock or second-degree heart block.
• Asthma: Use with caution in patients with reactive airway disease, as selectivity is dose-dependent.
• Pregnancy & Nursing: Use only when clearly prescribed by a physician.

Patient Advice

• Avoid sudden changes in posture to prevent orthostatic dizziness.
• Monitor your heart rate regularly and report bradycardia below 50 bpm to your doctor.
• Maintain a low-sodium diet and a healthy lifestyle.

Fact Box

Drug Interactions

• Calcium Channel Blockers (Verapamil, Diltiazem): May lead to severe bradycardia or heart block.
• NSAIDs (Ibuprofen): Can reduce the antihypertensive effect.
• Insulin: Beta-blockers may mask symptoms of hypoglycemia (tachycardia).

User Feedback

• Patients report highly satisfactory blood pressure control, with minimal fatigue compared to older beta-blockers.
• Highly recommended by clinicians as a reliable first-line antihypertensive therapy.