Product Introduction: CARVENOL -6.25

CARVENOL -6.25 is a widely prescribed non-selective beta-blocker with alpha-1 blocking activity manufactured by Knoll. Composed of 6.25mg of Carvedilol, this tablet is indicated for the treatment of essential hypertension, congestive heart failure, and left ventricular dysfunction post-myocardial infarction. It lowers blood pressure and cardiac workload.

Primary Indications

• Management of essential hypertension (high blood pressure).
• Treatment of mild-to-severe congestive heart failure of ischemic or cardiomyopathic origin.
• Management of left ventricular dysfunction following myocardial infarction.

Therapeutic Benefits

• Dual Action: Non-selective beta-blockade slows heart rate, while alpha-1 blockade causes peripheral vasodilation, lowering blood pressure.
• Cardioprotection: Reduces cardiac remodeling and improves survival in heart failure patients.
• Low Starting Dose: The 6.25mg strength is a recommended starting dose, reducing risks of initial orthostatic hypotension.

Possible Side Effects

Common side effects may include:

• Dizziness, fatigue, headache, or orthostatic hypotension.
• Bradycardia (slow heart rate) or transient worsening of heart failure.
• Hyperglycemia in diabetic patients or weight gain.

How to Take CARVENOL -6.25

• Take the tablet twice daily, with food to slow absorption rate and minimize orthostatic side effects.
• Swallow the tablet whole with a glass of water. Do not crush or chew.
• Do not stop taking the drug abruptly, as it can cause rebound hypertension or angina.

Mechanism of Action

CARVENOL -6.25 contains Carvedilol, which is a non-selective beta-adrenergic receptor antagonist and a selective alpha-1 adrenergic receptor antagonist. Alpha-1 blockade reduces systemic vascular resistance, and beta-blockade prevents reflex tachycardia and reduces myocardial work, lowering systemic blood pressure.

Safety Warnings

• Bradycardia: Contraindicated in patients with severe bradycardia, cardiogenic shock, or severe heart block.
• Asthma: Strictly contraindicated in bronchial asthma or COPD.
• Liver Impairment: Use caution; carvedilol is extensively cleared by the liver.

Patient Advice

• Avoid sudden changes in posture to prevent orthostatic dizziness.
• Monitor your blood pressure and heart rate regularly.
• Report any symptoms of fluid retention or worsening breathing issues immediately.

Fact Box

Drug Interactions

• Digoxin: May increase digoxin levels; monitor parameters closely.
• Calcium Channel Blockers (Verapamil): May lead to severe bradycardia or heart block.
• Insulin: Beta-blockers may mask symptoms of hypoglycemia.

User Feedback

• Heart failure patients report significant improvements in daily breathing comfort and stability.
• Highly recommended by cardiologists as a key life-saving cardiovascular therapy.