Product Introduction: HYDRONOL -12.5

HYDRONOL -12.5 is a widely prescribed thiazide diuretic tablet manufactured by Knoll. Composed of 12.5mg of Hydrochlorothiazide, it is indicated for the treatment of hypertension and edema associated with congestive heart failure, renal disease, or hepatic cirrhosis. It helps eliminate excess water and salt from the body.

Primary Indications

• Treatment of essential hypertension (high blood pressure).
• Treatment of edema associated with congestive heart failure.
• Management of fluid retention associated with renal or hepatic disorders.

Therapeutic Benefits

• Effective Fluid Clearance: Promotes water and sodium excretion, reducing swelling and volume overload.
• Antihypertensive Efficacy: Lowers systemic vascular resistance, helping manage blood pressure.
• Low Dose: The 12.5mg strength is a gentle dose with reduced metabolic side effects.

Possible Side Effects

Common side effects may include:

• Dehydration, dizziness, headache, or muscle cramps.
• Electrolyte imbalances, such as hypokalemia or hyponatremia.
• Mild digestive issues or elevated blood glucose levels.

How to Take HYDRONOL -12.5

• Take one tablet daily, preferably in the morning to avoid nocturnal urination.
• Swallow the tablet whole with a glass of water. Can be taken with or without food.
• Do not stop taking the drug without consulting your doctor.

Mechanism of Action

HYDRONOL -12.5 contains Hydrochlorothiazide, which inhibits the Na+/Cl- cotransporter in the renal distal convoluted tubule. This increases the excretion of sodium, chloride, and water, leading to a reduction in plasma volume and subsequent drop in blood pressure.

Safety Warnings

• Anuria: Contraindicated in patients with active anuria or severe renal failure.
• Electrolytes: Monitor electrolyte levels regularly, as potassium depletion can occur.
• Pregnancy & Nursing: Use only when clearly prescribed by a physician.

Patient Advice

• Avoid standing up too quickly from a sitting or lying position to prevent dizziness.
• Monitor your blood pressure and kidney parameters regularly.
• Maintain a balanced intake of potassium-rich foods like bananas.

Fact Box

Drug Interactions

• Lithium: Diuretics decrease lithium clearance, increasing toxicity risk.
• NSAIDs (Ibuprofen): Can reduce the diuretic and blood-pressure-lowering effects.
• Oral Antidiabetics: Hydrochlorothiazide may elevate blood glucose levels.

User Feedback

• Patients report highly satisfactory reduction in swelling and stable blood pressure management.
• Praised for its low dosage and high tolerability.