Product Introduction: CLOPICARD 75

CLOPICARD 75 is a widely prescribed antiplatelet medication manufactured by Cipla. Containing 75mg of Clopidogrel, this tablet is indicated for the secondary prevention of atherothrombotic events. By preventing blood clots from forming in narrowed arteries, it lowers the risk of heart attacks and strokes.

Primary Indications

• Prevention of myocardial infarction and ischemic stroke in patients with atherosclerosis.
• Management of acute coronary syndrome (ACS).
• Prevention of blood clot formation in patients post-cardiac stent placement.

Therapeutic Benefits

• Anti-Thrombotic Action: Highly effective in keeping blood flowing smoothly.
• Stent Maintenance: Crucial therapy to prevent stent occlusion post-angioplasty.
• Favorable Safety Profile: Well-tolerated for long-term clinical use.

Possible Side Effects

Common side effects may include:

• Bleeding tendencies, such as easy bruising or nosebleeds.
• Indigestion, diarrhea, or mild abdominal discomfort.
• Skin rash or pruritus.

How to Take CLOPICARD 75

• Take one tablet daily, with or without food, at the same time each day.
• Swallow the tablet whole with a glass of water.
• Do not stop taking the medication abruptly without consulting your cardiologist.

Mechanism of Action

CLOPICARD 75 contains Clopidogrel, which is a prodrug. It requires biotransformation by cytochrome P450 enzymes to produce its active metabolite. This active metabolite selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor, preventing ADP-mediated activation of the glycoprotein IIb/IIIa complex and blocking platelet aggregation.

Safety Warnings

• Bleeding Risk: Contraindicated in patients with active pathological bleeding (such as peptic ulcers or intracranial hemorrhage).
• Pregnancy & Nursing: Use only if clearly prescribed by a physician.
• Surgery: Discontinue the medication 5-7 days before scheduled elective surgeries.

Patient Advice

• Inform all healthcare providers (including dentists) that you are taking this antiplatelet medication.
• Use caution when shaving or using sharp objects to avoid cuts.
• Report any unexplained blood in the urine or stool immediately.

Fact Box

Drug Interactions

• Proton Pump Inhibitors (Omeprazole, Esomeprazole): May reduce Clopidogrel activation and effectiveness.
• NSAIDs (Ibuprofen): Significantly increase the risk of gastrointestinal bleeding.
• Oral Anticoagulants (Warfarin): Elevates risk of major bleeding events.

User Feedback

• Patients value the reliable prevention of arterial thrombosis, especially after stent placement.
• Highly recommended by cardiologists for long-term antiplatelet protection.